- Preston, the lowest-ranked team still in, entertain Aston Villa
- Manchester City travel to Bournemouth
- Fulham host London rivals Crystal Palace

The FA Cup quarter-finals take centre stage this weekend with a place in the last four and a trip to Wembley up for grabs.

Seven of the eight sides still left in the competition are from the Premier League, but none of Bournemouth, Brighton, Crystal Palace and Fulham have ever lifted the FA Cup before.

Preston North End, who are in the quarter-finals for the first time since 1966, are representing the Championship.

We look ahead to a big weekend of FA Cup action and have a score prediction for all four ties.

Fulham vs Crystal Palace (Saturday, 12.15pm)

London rivals Fulham and Crystal Palace are set to play out a closely-fought quarter-final at Craven Cottage as they both look to stay on course for a first-ever FA Cup triumph.

Palace have been in fine form recently, winning their last four games, and they will be tough opponents for Marco Silva's men but the hosts are tipped to progress on penalties – just like they did in the previous round against Manchester United – after a tight and tense 120 minutes.

Score prediction: Fulham 1-1 Crystal Palace (Fulham to win on penalties)

Brighton vs Nottingham Forest (Saturday, 5.15pm)

Since Brighton were humbled 7-0 by Nottingham Forest at the City Ground at the start of February in the league, they have gone on a seven-game unbeaten run, winning six of those matches.

During that recent period they secured eye-catching victories over Newcastle and Chelsea in the FA Cup and the Seagulls can now book themselves a semi-final place at Forest's expense.

Score prediction: Brighton 3-1 Nottingham Forest

Preston North End vs Aston Villa (Sunday 1.30pm)

Preston are the only non top-flight team left in the competition, but they look set to be thwarted in their bid to make the last four for the first time in 61 years by Aston Villa.

Unai Emery's side have won three of their last four games in all competitions without conceding a goal and they are enjoying another good season.

They remain in the hunt for a top-four finish in the league and also have a huge Champions League quarter-final against Paris Saint-Germain to come next month.

Score prediction: Preston North End 0-2 Aston Villa

Bournemouth vs Manchester City (Sunday, 4.30pm)

Manchester City's poor season could yet end with FA Cup glory and the seven-time winners should get revenge for their Premier League defeat at Bournemouth earlier in the season by securing a semi-final place.

The Cherries' only victory in their last five outings came against Wolves in the previous round when they won on penalties and even though City have lost to Nottingham Forest and drawn with Brighton in their last two matches, Pep Guardiola's side can edge what is set to be tight tie.

Score prediction: Bournemouth 1-2 Manchester City