Dominic Thiem has been ruled out of Wimbledon after tests on a wrist injury and faces a race to be fully fit in time to defend his US Open title.

The world number five retired from his match against Adrian Mannarino in the Mallorca Championships on Tuesday, when 5-2 up in the opening set.

Checks on the wrist by a specialist in Barcelona have shown Thiem needs time away from tennis, meaning Wimbledon is off the table along with tournaments in Hamburg and Gstaad in July.

According to a medical bulletin issued on Thiem's social media accounts, it will be five weeks before he can remove a wrist splint and begin to step up his recovery.

With the US Open beginning on August 30, that does not leave a lot of time for Thiem to recover physical fitness and find his best tennis. He would have been seeded number four at Wimbledon.

The medical bulletin read: "Tests found that there is a 'detachment of the posterior sheath of the ulnar side of the right wrist', an injury that will not allow him to compete in the circuit for several weeks.

"Thiem will wear a wrist splint for five weeks before beginning a progressive process of specific, functional rehabilitation to regain mobility as well as muscle strength in his wrist and ultimately return to training on court."

Thiem, who had already decided against playing at the upcoming Tokyo Olympics, appears to be hoping his lay-off is not as long as the experts have forecast.

He will undergo MRI scans and tests as his recovery progresses, and the 27-year-old Austrian said: "I'm going to do everything the doctors say in order to recover as quickly as possible.

"They've informed me that I might be out for several weeks, but I will do my best to be back on court soon.

"I'm really sorry for pulling out of the upcoming three tournaments I had in my calendar: Wimbledon, Hamburg and Gstaad.

"They are very important tournaments for me. I appreciate all the support from the fans in these difficult moments – I'm determined to come back stronger."

Thiem's absence is another blow for Wimbledon, with Rafael Nadal and Naomi Osaka having already announced they would not be playing the tournament.