- Top two meet at the Etihad as Man City and Arsenal clash on Sunday
- Two of the bottom six clash on Saturday, with Leicester facing Everton
-  Newcastle look to extend their unbeaten start to five matches

West Ham vs Chelsea (Saturday, 12:30pm)

Chelsea look to have found their feet, having collected seven points in their last three league games, while West Ham have lost both of their home games this season.

It’s also worth noting that nine of Chelsea’s last 11 league away games have had four or more goals.

Score prediction: West Ham 2-3 Chelsea

Aston Villa vs Wolves (Saturday, 3pm)

Both teams had midweek fixtures, although Wolves were able to rotate a number of their first-team regulars.

Both teams have scored in Villa’s last five league home games, while two of the last four meetings between these Midlands rivals have been draws.

Score prediction: Aston Villa 1–1 Wolves

Fulham vs Newcastle (Saturday, 3pm)

Newcastle have won on their last five trips to Craven Cottage and head to West London looking for a third straight league win.

Fulham haven’t kept a clean sheet in any of their last six Premier League home games.

Score prediction: Fulham 1-2 Newcastle

Leicester vs Everton (Saturday, 3pm)

Both teams threw away two-goal leads last week and neither team have been able to keep a clean sheet this season.

Everton have lost nine of their last 12 away games, while three of the last five meetings between these teams have finished in draws.

Score prediction: Leicester 1-1 Everton

Liverpool vs Bournemouth (Saturday, 3pm)

In their last five meetings at Anfield, Liverpool lead by an aggregate score of 20-2 and the Reds have won the last three games against Bournemouth.

The visitors have won just three of their last 12 Premier League away games.

Score prediction: Liverpool 3–1 Bournemouth

Southampton vs Ipswich (Saturday, 3pm)

Ipswich did the double over Southampton in the Championship last term, but there was only one goal in it on both occasions.

The visitors head to St Mary’s after three successive draws in all competitions, while Saints are still seeking their first point.

Score prediction: Southampton 1-1 Ipswich

 Tottenham vs Brentford (Saturday, 3pm)

There have been over two goals in 17 of Tottenham’s last 19 Premier League home games and Brentford have conceded in every one of their opening five league matches.

Yoane Wissa’s injury setback could be a major blow to the Bees, who lost 3-2 in this fixture last season.

Score prediction: Tottenham 3-1 Brentford

Crystal Palace vs Man Utd (Saturday, 5:30pm)

Palace did the double over United last season and have not lost to the Red Devils on home soil since 2020.

Although there have been signs of improvement from United, they have won just two of their last eight league games on the road.

Score prediction: Crystal Palace 1-1 Man Utd

Brighton vs Nottingham Forest (Sunday, 2pm)

These two teams remain unbeaten after four matches and this is likely to be a tight encounter.

Brighton won this fixture 1-0 last season and it would be no surprise to see a similar scoreline this time.

Score prediction: Brighton 1-0 Nottingham Forest

Man City vs Arsenal (Sunday, 4:30pm)

Two of the last three meetings between City and Arsenal have ended in draws, including this fixture last season (0-0).

After a week of facing Tottenham and Atalanta away from home, the Gunners would take another point in order to stay on the coattails of City, who haven’t lost a home league game since November 2022.

Score prediction: Man City 1-1 Arsenal