Anthony Gordon’s sixth goal of the season handed Newcastle a sixth-successive Premier League victory at St James’ Park as Manchester United became their latest victims.

The Magpies, who returned from Paris St Germain in midweek bitterly disappointed with a 1-1 Champions League draw, dominated for all but the final few minutes and perhaps should have secured the points in more emphatic fashion with Kieran Trippier seeing a first-half free-kick come back off the crossbar.

However, Gordon’s 55th-minute finish – the fourth-successive home league game in which he has scored – proved sufficient to clinch a 1-0 win and send Eddie Howe’s side above the Red Devils in the table, although his joy was tempered by a potentially-serious injury to goalkeeper Nick Pope.

Manchester United, who had thrown away a 3-1 lead at Galatasaray to draw 3-3 on Wednesday evening, created little of note – they saw a late goal ruled out after Antony’s shot had clipped Harry Maguire in an offside position – as their run of five wins in six league games came to an end in front of a crowd of 52,214.

Under-fire goalkeeper Andre Onana and Diogo Dalot got themselves in a tangle as they attempted to deal with a Gordon cross, although opposite number Pope had to repel Alejandro Garnacho’s 11th-minute attempt with a well-placed foot after Bruno Fernandes’ superb pass had played him in behind Trippier.

Garnacho became an increasing threat down the Magpies’ right as Manchester United started to impose themselves, but Luke Shaw had to block Alexander Isak’s 15th-minute effort after Trippier had fizzed the ball into his feet inside the penalty area.

Onana saved from Miguel Almiron following a neat one-two between Joelinton and Trippier, while Guimaraes smashed an 18th-minute shot over from distance after Tino Livramento had surged forward down the left and cut the ball back.

The visitors were creaking and Maguire had to be in the right place at the right time to deflect Isak’s goal-bound effort wide before Jamaal Lascelles headed over from the resulting corner.

Playmaker Fernandes did his best to drag Erik ten Hag’s men into the game, but too often the men ahead of him were not equal to the task and they continued to look less than certain at the back with Isak firing wide 12 minutes before the break after Aaron Wan-Bissaka had headed Fabian Schar’s long ball straight to him.

Almiron curled an attempt over the angle of post and crossbar after cutting inside Dalot from Trippier’s through-ball, but Onana enjoyed the kind of fortune which has eluded him in recent weeks when Trippier rattled the crossbar with a 39th-minute free-kick after Maguire had felled Schar 25 yards out.

Livramento, whose scything run led to Isak’s goal at Paris St Germain, almost repeated the dose two minutes after the restart when he set up Almiron, but saw the Paraguay international’s shot half-blocked to allow Onana to save comfortably.

The keeper was finally beaten seconds later when Guimaraes rolled the ball into Trippier’s path and he crossed low to the far post for Gordon to score.

Schar whistled a shot from distance a foot over Onana’s crossbar as the home side looked to kill the game off, and Ten Hag responded by replacing Marcus Rashford and Martial with Antony and Rasmus Hojlund.

Antony added vigour to a side in desperate need of inspiration, but to little real effect and Wan-Bissaka survived penalty appeals for handball after blocking Lewis Miley’s shot with 12 minutes remaining.

Schar had to throw his body into the path of Sergio Reguilon’s well-struck 82nd-minute volley, although Pope’s evening ended in agony as he was led from the pitch having suffered an injury as he dived in anticipation behind the defender.

Replacement Martin Dubravka was beaten with two minutes of normal time left on the clock, but an offside flag came to the tiring Magpies’ rescue and they safely negotiated nine minutes of stoppage-time to claim victory.