Carabao Cup draw: Chelsea face Toon as Reds host Hammers in last eight
Chelsea will face Newcastle while Liverpool go head-to-head with West Ham in the quarter-finals of the Carabao Cup.
Another all-Premier League tie sees Everton host Fulham after seeing off Burnley and Ipswich respectively.
Meanwhile, League One Port Vale will host Championship Middlesbrough as the EFL duo compete for a place in the semi-finals.
The Magpies have thrillingly seen off both Manchester City and Manchester United on their way to this stage and they now must get a result at Stamford Bridge in their efforts to go one better than last season's defeat in the final.
The Blues were comfortable 2-0 winners over Blackburn as Mauricio Pochettino looks to mark the start of his era with their first trophy under Todd Boehly's ownership.
Liverpool saw off Bournemouth at a wet and windy Vitality Stadium and must now face the Hammers, who were dominant winners over Arsenal.
The Carabao Cup quarter-finals are guaranteed to have representation from the EFL, with Port Vale reaching this stage for the first time in their history after beating Mansfield.
They have been rewarded with a tie against Boro, who were 3-2 winners over Exeter on Tuesday.
Carabao Cup quarter-final draw in full
Everton vs Fulham
Chelsea vs Newcastle
Port Vale vs Middlesbrough
Liverpool vs West Ham